Group Member: Michaela Gruber

Contact Details

Research Interests

I have focused my research on chronic lymphocytic leukemia (CLL), a clinically heterogeneous malignancy which can remain asymptomatic for a long time while other cases progress rapidly. The high frequency of CLL and availability of highly pure tumor samples provide opportunities for genetic and epigenetic studies which are unique across cancers. By learning what drives CLL heterogeneity we can thus find insights that aid to understand not only CLL but cancer in general. Currently I am most interested in the interaction of epigenetics with somatic genetic evolution to understand cancer initiation and early development.  Thus, I am thrilled by the opportunity to bring together unique CLL sample collections from the Vienna General Hospital with powerful sequencing technologies and bioinformatic pipelines established at Christoph Bock’s lab. In addition, I have previously developed experimental (in vitro and in vivo) CLL and B-cell models that enable me to pursue a variety of functional studies.

Academic Employment

Academic Degrees

Scholarships and Awards

Fellowships and Grants


Selected Publications